GC from Columbia, Mo. on 2/6/2007 7:11:43 AM:
It really depends on what you want to see. The western leg (Clinton to Boonville) is farmland, rolling hills, long stretches across prairies and through woods. The eastern leg (New Franklin to St. Charles) is entirely in the river bottoms, with lots and lots of corn and soybean fields on one side, broken up by views of the river, and some pretty majestic river bluffs on the other. You really should see it all.
If I had to chose, though, I would hit the trail in the Boonville/Rocheport area and head east to at least the McKittrick/Augusta area