Paul Toigo on 7/29/2008 5:39:51 PM:
Indeed, while their website indicates that the route is mapped South of Hannibal, the directions start from St. Louis and go South.
http://www.mississippirivertrail.org/
The Mississippi River Trail, coursing along America’s backbone, the Mississippi River, from its headwaters in Itasca, Minnesota to the Gulf of Mexico, offers approximately 3,000 miles of on-road and bike/pedestrian pathways for the recreational enjoyment, health, conservation, and tourism development of river communities, river states, and the nation.