JPM from Hazelwood, MO on 5/24/2011 5:59:42 PM:
From the airport in STL, you can take the MetroLink (www.metrostlouis.org) light rail to the Civic Center station. Metro is bike friendly, but they ask that you to board at the front or rear of the train. After you depart the MetroLink, you can walk over to the Amtrak station. You can bring your bikes on Amtrak, but it will cost you an additional $10 per bike. You can take the Missouri River Runner Amtrak train to Sedalia and access the trail there. I'm not aware of any shuttle to Clinton, perhaps folks from that end of the trail can provide more info.