kevin from Jeff City on 7/23/2012 1:48:53 PM:
Just to throw in another qualifier: if you are planning to carry your own gear, get a little bigger tire, at least on your rear wheel.
I ran into a couple going from Jefferson City to Boonville on road bikes Sunday, and he was stuck with multiple flats right outside of Hartsburg. He was carrying stuff in panniers, and that may have been stressing his tires.
If you aren't carrying anything, then rock on, especially now. The trail is hard-packed with the lack of rain.