Darrell from Jefferson City, Mo. on 5/27/2013 2:17:55 AM:
Maybe others know of something you would miss out on by starting in Mokane, but I can't think of anything other than the scenery, which is pretty much the same heading east from Mokane. Oh, and if you are lucky, you might be able to get a soda or beer in Tebbets but you can't count on it. The distance difference is 6 miles closer to St. Charles.
And, what Denbo said! Saddle time is the best prep you can do. Just did back to back 40+ mile days, normally no biggie, but having not ridden much this year, that part that comes into contact with the saddle sure is sore.