kevin from Jeff City on 9/3/2013 1:37:44 PM:
Ditto on ditching the knobbies. A good set of road tires with some puncture resistance will make it a more enjoyable experience.
That being said, you can ride with knobbies, but they will slow you down.
Also, consider a rack and panniers, or a trailer if you are hauling camping gear. A backpack over distances is a recipe for back pain.